6th International Conference on Lung & Respiratory Disease
Paris, France
Dr. Anil Bhatta
PROFESSOR & HEAD, DEPARTMENT OF MEDICAL BIOCHEMISTRY GOVT.MEDICAL COLLEGE, AMRITSAR
Title: NASAL EPITHELIAL CELLS TO ASSESS IN VITRO IMMUNE RESPONSES TO RESPIRATORY VIRUS INFECTION IN PREGNANT WOMEN WITH ASTHMA
Biography
Biography: Dr. Anil Bhatta
Abstract
Respiratory virus-induced asthma exacerbations occur frequently during pregnancy and are associated with adverse outcomes for mother and child. Primary nasal epithelial cells (pNECs) provide a useful method to study immune responses in pregnancy. PNECs were obtained by nasal brushings from pregnant and non-pregnant women with and without asthma. PNECs were infected in vitro with major group Rhinovirus 43 (RV43) and seasonal influenza (H3N2). Following infection, pNECs showed measurable quantities of interferon (IFN)-λ, IL-1β, IL-8, IP-10 and MIP1-α. PNECs provide a safe and effective method for studying respiratory epithelial cell responses during pregnancy.