Robert Lins
SGS Clinical Research
Title: Trends in the use of outcome parameters for respiratory drug research.
Biography
Biography: Robert Lins
Abstract
Substantial success has been realized in the treatment respiratory diseases due to more insight in the mechanisms of disease like inflammatory pathways and new targets for treating these diseases. However there is a clear discrepancy between the outcome parameters, currently used in clinical studies, and clinical outcome and survival. So, there is an unmet need for additional more sensitive outcome parameters that would assist in understanding the mode of action and subsequent pharmacodynamics effects. The ever rising costs and attrition rate of developing new respiratory drugs, makes it mandatory to increase the performance of clinical trials by using these methods and by more efficient study designs.